Publications sur les instruments

Trouvez les produits ChemoMetec dans les publications scientifiques à comité de lecture

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Type de recherche

2022

Genotoxic and inflammatory effects of spruce and brown coal briquettes combustion aerosols on lung cells at the air-liquid interface

  • Ihantola T, Hirvonen MR, Ihalainen M, et al. ,

  • Science of The Total Environment ,

  • 2022,

  • 860;150489

  • Instrument: NucleoCounter® NC-3000™
  • Type de recherche: Cell Biology

Solid fuel usage in residential heating and cooking is one of the largest sources of ambient and indoor air particulate matter, which causes adverse effects on the health of millions of peoples worldwide. Emissions from solid fuel combustion, such as...

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Potential Anticancer Agents against Melanoma Cells Based on an As-Synthesized Thiosemicarbazide Derivative

  • Kozyra P, Korga-Plewko A, Karczmarzyk Z, et al. ,

  • Biomolecules ,

  • 2022,

  • 12(2):151

  • Instrument: NucleoCounter® NC-3000™
  • Type de recherche: Oncology

In this paper, thiosemicarbazide derivatives were synthesized as potential anticancer agents. X-ray investigations for 1-(2,4-dichlorophenoxy)acetyl-4-(2-fluorophenyl) thiosemicarbazide, 1-(2,4-dichlorophenoxy)acetyl-4-(4-metylothiophenyl)thiosemicarbazide and 1-(2,4-di chlorophenoxy)acetyl-4-(4-iodophenyl)thiosemicarbazide were carried out in order to confirm the synthesis pathways, identify their tautomeric forms, analyze the conformational preferences of molecules,...

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  • Instrument: NucleoCounter® NC-3000™
  • Type de recherche: Oncology

Malignant melanoma is still a serious medical problem. Relatively high mortality, a still-growing number of newly diagnosed cases, and insufficiently effective methods of therapy necessitate melanoma research. Tetracyclines are compounds with pleiotropic pharmacological properties. Previously published studies on melanotic melanoma...

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2021

  • Instrument: NucleoCounter® NC-3000™
  • Type de recherche: Cell Biology

Measured variability of product within Cell and Gene Therapy (CGT) manufacturing arises from numerous sources across pre-analytical to post-analytical phases of testing. Operators are a function of the manufacturing process and are an important source of variability as a result...

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  • Instrument: NucleoCounter® NC-3000™
  • Type de recherche: Cell Biology

Previous studies revealed that direct contact with graphene oxide (GO) induced cytotoxic effects, but the importance of involvement of metabolic pathways, in particular lipid metabolism pathways, might be overlooked. In this study, human umbilical vein endothelial cells (HUVECs) were exposed...

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  • Instrument: NucleoCounter® NC-3000™
  • Type de recherche: Cell Biology

Oxidative stress has been implicated in the pathogenesis of Alzheimer’s disease (AD). Mitochondrial dysfunction is linked to oxidative stress and reactive oxygen species (ROS) in neurotoxicity during AD. Impaired mitochondrial metabolism has been associated with mitochondrial dysfunction in brain damage...

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2020

The calcium-sensing receptor is essential for calcium and bicarbonate sensitivity in human spermatozoa

  • Boisen IM, Rehfeld A, Mos I, et al. ,

  • The Journal of Clinical Endocrinology and Metabolism ,

  • 2020,

  • dgaa937

  • Instrument: NucleoCounter® NC-3000™
  • Type de recherche: Animal Reproduction

Context: The calcium-sensing receptor (CaSR) is essential to maintain a stable calcium concentration in serum. Spermatozoa are exposed to immense changes in concentrations of CaSR ligands such as calcium, magnesium, and spermine during epididymal maturation, in the ejaculate, and in...

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  • Instrument: NucleoCounter® NC-3000™
  • Type de recherche: Brewing

Cellular senescence is defined by irreversible cell-cycle arrest and is an evolutionarily conserved hallmark of aging. In this study, we generate senescent microglial cells via exposure to the chemotherapy drug doxorubicin. Compared to control cells, doxorubicin-treated microglia exhibited an altered...

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Characterization of Human Mitochondrial PDSS and COQ Proteins and Their Roles in Maintaining Coenzyme Q 10 Levels and Each Other’s Stability

  • Hsiu-Chuan Yen , Wen-Yu Yeh , Szu-Hsien Lee , et al. ,

  • Biochim Biophysica Acta Bioenergetics ,

  • 2020,

  • 1861(7):148192

  • Instrument: NucleoCounter® NC-3000™
  • Type de recherche: Cell Biology

Mutations of many PDSS and COQ genes are associated with primary coenzyme Q10 (CoQ10) deficiency, whereas mitochondrial DNA (mtDNA) mutations might cause secondary CoQ10 deficiency. Previously, we found that COQ5 and COQ9 proteins are present in different protein complexes in...

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